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Novel Selective Activators of Neuronal GIRK Heteromeric Channels Effective in Animal Models of Post-Traumatic Stress Disorder

-collapse: collapse; } INV-18111 Background G protein-gated inwardly rectifying potassium (GIRK) channels, are channels distributed throughout the central nervous system as well as the heart. Pharmacological investigations of GIRK channels, along with studies in animal models, suggest that GIRK activity has an important role in physiological...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Ganeshsingh Thakur, Diomedes Logothetis, Anantha Shekhar, Yu Xu, Lucas Cantwell

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Category(s): Technology Classifications > 1. Life Science > Therapeutics