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Grayscale photolithography method for graded apertures for electrophysiology and nanopore sensing measurements
INV-20026 Background Lipid membranes are widely used in the pharmaceutical industry and research areas to study the impact of various drugs on protein channels, which are often drug targets. The proposed process to form angled apertures can be used for various applications, such as to make a pillars-on-wedge aperture that supports lipid membranes...
Published: 1/27/2025
|
Updated: 3/21/2024
|
Inventor(s):
Meni Wanunu
,
Mohammadamin Alibakhshi
,
Xinqi Kang
Keywords(s):
lipid membranes
,
Nanopores
Category(s):
-Nanotechnology
Electrically Actuatable Zero-mode Waveguides for High-Throughput pg-Level Sequencing
INV-20008 Background DNA sequencing technologies have undergone tremendous improvements in recent years in throughput and quality. One advantage of single-molecule DNA sequencing technologies is that long DNA molecules can be read in a single run, which greatly facilitates genome assembly and aids in the construction of reference-quality genomes....
Published: 1/27/2025
|
Updated: 3/21/2024
|
Inventor(s):
Meni Wanunu
,
Mohammadamin Alibakhshi
,
Fatemeh Farhangdoust
Keywords(s):
DNA sequencing
,
single-molecule
Category(s):
Technology Classifications > 1. Life Science
,
Technology Classifications > 1. Life Science > Biotechnology
,
Technology Classifications > 1. Life Science > Gene sequencing
,
Chemistry
Bead-barcoded digital quantifiers of molecular species
INV-18085 Background A problem plaguing health in society today is a need for rapid tools for accurate diagnosis of disease. Early signs of cancers, infections, and other diseases are typically accompanied by molecular indicators called as biomarkers, that are often too low in abundance to quantify using conventional techniques. Protein biomarkers...
Published: 1/27/2025
|
Updated: 3/21/2024
|
Inventor(s):
Meni Wanunu
,
Mohammadamin Alibakhshi
Keywords(s):
Category(s):
Diagnostics
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