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A Minimal Cell Lysis and Bottom-up Proteomics Sample Preparation Technique
INV-18031 Background Quantifying proteins in limited samples are required for many practical applications, including biopsies, tissue samples, clinical trial of pharmaceuticals, and others. Several methods have been developed for doing sample prep with minimal losses. However, all existing methods uses a chemical that undermines mass-spec analysis...
Published: 1/27/2025
|
Updated: 3/21/2024
|
Inventor(s):
Nikolai Slavov
,
Bogdan Budnik
,
Harrison Specht
Keywords(s):
Category(s):
Technology Classifications > 1. Life Science
,
Technology Classifications > 1. Life Science > Drug Discovery
,
Diagnostics
,
Chemistry
Ultrasensitive and High-Throughput Quantification of Post-translational Modifications of Proteins by Mass Spectrometry
INV-18021 Background Advances in single-cell RNA-sequencing (transcriptomics) and genomics have been instrumental in our understanding of gene expression and human disease. While advancements have been made in single-cell protein analysis, state of the art technologies still have significant limitations. Most proteomic methods rely on antibodies...
Published: 1/27/2025
|
Updated: 3/21/2024
|
Inventor(s):
Nikolai Slavov
,
Bogdan Budnik
,
Ezra Levy
Keywords(s):
Category(s):
Technology Classifications > 1. Life Science > Drug Discovery
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