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Novel Allosteric Modulators of CB1 Cannabinoid Receptor

Background A novel class of compounds containing indole functionality has been found to have robust positive allosteric modulator (PAM) activity at the CB1 cannabinoid receptor. GAT1102 is a representative compound from this class shown to be effective in lowering intraocular pressure in the animal model with potential utility in treating glaucoma. ...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Ganeshsingh Thakur, Sumanta Garai

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Category(s): Technology Classifications > 1. Life Science > Biotechnology