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Site-specific Modification of Antibody through a Tranglutaminase-mediated Conjugation of Glutamine While Maintaining the Core Glycan
Site-specific Modification of Antibody through a Transglutaminase-mediated Conjugation of Glutamine While Maintaining the Core Glycan Technical advancement of site-specific antibody engineering creating more homogenous biologics Institute Reference: INV-21035 Background Antibodies are a predominant class of macromolecules with wide-spread...
Published: 1/27/2025
|
Updated: 3/21/2024
|
Inventor(s):
Zhaohui Zhou
,
Amissi Sadiki
Keywords(s):
Antibody conjugates
,
Endoglycosidase
,
Glycan remodeling
,
Glycoengineering
,
Transglutaminase
Category(s):
Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering
,
Technology Classifications > 1. Life Science > Biotechnology
,
Diagnostics
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