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Making Oligonucleotides Better Biopharmaceuticals with Brush Polymer-Assisted Compaction

INV-16006 Background Oligonucleotide-based gene therapy holds tremendous promise for treating a variety of disorders with a genetic basis, including cancers, neurological diseases, and metabolic conditions. However, due to difficulties including poor accumulation at target sites, removal by immune responses, nuclease degradation, and low biochemical...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Ke Zhang, Xueguang Lu

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Category(s): -Cancer, -Chemistry, Technology Classifications > 1. Life Science, Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Drug Delivery