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Nanopore and membrane protein dynamic multichannel measurement apparatus and fabrication method for same
INV-23089 Background: Nanopore sensing devices are integral to scientific research and applications such as DNA sequencing and protein detection. The dynamic of trans and cis user access to a membrane in such devices can, however, pose significant challenges. Fulfilling the need for multiplexed and scalable nanopore sensing systems, especially those...
Published: 1/27/2025
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Updated: 3/21/2024
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Inventor(s):
Meni Wanunu
,
Ali Fallahi
,
Amr Makhamreh
Keywords(s):
Biosensing
,
Drug Discovery
,
Microfluidics
,
Nanopores
,
Protein sequencing
Category(s):
Technology Classifications > 1. Life Science
,
Technology Classifications > 2. Physical Science
,
Technology Classifications > 1. Life Science > Gene sequencing
,
Diagnostics
Reversible Microwells for Single Cells Culture and Recovery
INV-20077 Background Microwells are popular single cell-level culture platforms where small wells of tens of microns in size are able to hold only one cell or cell pairs according to the scope. Arrays of these wells are useful to separate cell populations and culture or image them. However, these wells are monolithic and normally engraved in the...
Published: 1/27/2025
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Updated: 3/21/2024
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Inventor(s):
Giovanni Ugolini
,
Tania Konry
Keywords(s):
Genome
,
Healthcare Innovation
,
Immunoengineering
,
Microarray
,
Microfluidics
,
Singe cell
Category(s):
Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering
Novel bioassay platform for drug and immunotherapy screenings in a personalized format for highly functional cell expansion
INV-19076 Background Immunological screenings for different infections and cancers can yield essential information for developing effect treatments. The efficiency and accuracy of screenings can be improved by choosing efficient matrices and type of assay. Different 3D matrices have been used for immunological screenings. However, due to limited...
Published: 1/27/2025
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Updated: 3/21/2024
|
Inventor(s):
Giovanni Ugolini
,
Tania Konry
Keywords(s):
Analytical Chemistry
,
Assays
,
Detection
,
Immunological/Autoimmune Disease
,
Microfluidics
Category(s):
-Biomedical Materials
,
-Cancer
,
-Chemistry
,
-Devices
,
-Equipment
Functional phenotyping of cells in droplet based platforms
INV-16003 Background Recently, the development of microfluidic, technology-enabled analysis of cell phenomena on the single-cell level has been a growing area of research within the academic realm. Current microfluidic platforms based on micro-well technologies do not provide a robust protocol for cell co-encapsulation in a controllable microenvironment,...
Published: 1/27/2025
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Updated: 3/21/2024
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Inventor(s):
Tania Konry
,
Saheli Sarkar
Keywords(s):
Diagnostics
,
Microfluidics
,
Singe cell
Category(s):
-Microbiology
,
Technology Classifications > 1. Life Science > Therapeutics
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