Search Results - diagnostics

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Antibody-based Rolling Circle Amplification for COVID-19 Detection by a Colorimetry

INV-21038 Background Viruses are conventionally detected by RT-PCR. This method requires long analysis time, highly trained professionals, and often shows non-specific characteristics. Antigens and antibodies (Ag/Ab) are commonly used for fluorescence immunoassay. However, the fluorescent signal from the individual fluorescent molecule attached...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Ji Won Lim, Tania Konry

Keywords(s): Analytical Chemistry, COVID-19, Detection, Diagnostics

Category(s): -Method, Technology Classifications > 1. Life Science, Diagnostics, Chemistry

Functional phenotyping of cells in droplet based platforms

INV-16003 Background Recently, the development of microfluidic, technology-enabled analysis of cell phenomena on the single-cell level has been a growing area of research within the academic realm. Current microfluidic platforms based on micro-well technologies do not provide a robust protocol for cell co-encapsulation in a controllable microenvironment,...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Tania Konry, Saheli Sarkar

Keywords(s): Diagnostics, Microfluidics, Singe cell

Category(s): -Microbiology, Technology Classifications > 1. Life Science > Therapeutics

Instrumentation amplifier with built-in digitally-programmable input capacitance cancellation

INV-14068 Background Battery-powered portable or implantable biopotential and bioimpedance measurement devices are becoming increasingly widespread in the medical diagnostics field. The signal acquisitions of the main biosignal-sensing applications such as electroencephalography (EEG) and electrocardiography (ECG) involve voltage measurements from...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Marvin Onabajo, Chun-hsiang Chang

Keywords(s): Diagnostics, Health, Medical Device

Category(s): -Health, Technology Classifications > 1. Life Science > Medical Devices, Diagnostics

Chemical Sensing with Fibrous Materials

INV-14037 Background Conventionally, various types of sensor elements have been used for detection of physiological analytes. Some of the most common ones are nanosensors and microworms. In vivo use of nanosensors has been limited by cellular uptake and diffusion into biological systems. Microworm sensors can overcome such limitations of nanosensors;...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Heather Clark, Timothy Ruckh, Mary Katharine Balaconis

Keywords(s): Diagnostics, Materials, Nanotechnology, Sensor Technology

Category(s): -Sensors tech, -Nanotechnology, -Materials, Diagnostics

Radionuclidic and Non-radionuclidic Molecular Imaging Agents for the Estrogen Receptor Based on 11-beta Subsituted Steroidal Anti-Estrogens

INV-13041 Background Breast cancer has become the most common cancer globally as of 2021, accounting for 12% of all new annual cancer cases worldwide, according to the World Health Organization. Among patients with breast cancer, approximately 75% have elevated expression of estrogen receptor (ER). Knowing the hormone receptor status of cancer is...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Robert Hanson, Kinh-Luan (Lenny) Dao

Keywords(s): Cancer, Chemistry, Diagnostics, Health, Medical imaging, Medical/Health, Science/Research

Category(s): -Health, Technology Classifications > 3. Computer Science > Imaging, Diagnostics, Technology Classifications > 1. Life Science > Theragnostic

Sealable Microvalve That Can Be Repeatedly Opened and Sealed

ink;color: #0000FF;text-decoration: underline; } INV-1243 Background The typical structure for a MEMS microvalve includes an orifice and a moveable plate that can be actuated to press against the orifice. When the plate does not press against the orifice, fluid can flow through the orifice and therefore through the valve. When the plate is pressed...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Carol Livermore, Chenye Yang

Keywords(s): Chemistry, Diagnostics, Environment, Homeland Security, Sensor Technology

Category(s): -Chemistry, -Equipment, -Homeland Security, -Sensors tech, -Health, Diagnostics, Technology Classifications > 2. Physical Science > Environmental/Clean tech, Technology Classifications > 2. Physical Science > Lab tech/equipment