Search Results - analytical+chemistry

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Antibody-based Rolling Circle Amplification for COVID-19 Detection by a Colorimetry

INV-21038 Background Viruses are conventionally detected by RT-PCR. This method requires long analysis time, highly trained professionals, and often shows non-specific characteristics. Antigens and antibodies (Ag/Ab) are commonly used for fluorescence immunoassay. However, the fluorescent signal from the individual fluorescent molecule attached...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Ji Won Lim, Tania Konry

Keywords(s): Analytical Chemistry, COVID-19, Detection, Diagnostics

Category(s): -Method, Technology Classifications > 1. Life Science, Diagnostics, Chemistry

Photo-Cation Enhanced Detection

gn:justify"> Background There are certain limitations and challenges posed by the use of mass spectrometry for analysis of small organic molecules in complex samples. Among the limiting factors are the requirement for multiple procedures and/or instrumentation, use of high temperatures, lack of sensitivity, and incomplete detection. High temperatures...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Roger Giese, Pushkar Kulkarni

Keywords(s): Analytical Chemistry

Category(s): -Chemistry

Novel bioassay platform for drug and immunotherapy screenings in a personalized format for highly functional cell expansion

INV-19076 Background Immunological screenings for different infections and cancers can yield essential information for developing effect treatments. The efficiency and accuracy of screenings can be improved by choosing efficient matrices and type of assay. Different 3D matrices have been used for immunological screenings. However, due to limited...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Giovanni Ugolini, Tania Konry

Keywords(s): Analytical Chemistry, Assays, Detection, Immunological/Autoimmune Disease, Microfluidics

Category(s): -Biomedical Materials, -Cancer, -Chemistry, -Devices, -Equipment

Method and Device for Drug Discovery

INV-1253 Background Historically, natural products and microorganisms have been considered as the major sources of new pharmaceutical compounds. However, in recent years, there has been a dramatic drop in natural-based drug discovery from big pharmaceutical companies. The major challenges are the prevailing paradigm for drug discovery in large pharmaceutical...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Slava Epstein

Keywords(s): Analytical Chemistry, Biotech, Drug Discovery & Development, Infectious Disease (including AIDS), Process, Research Tool

Category(s): -Microbiology, -Analytical Chemistry, -Health, Technology Classifications > 1. Life Science > Drug Discovery, Technology Classifications > 2. Physical Science > Lab tech/equipment

Hydrogel with Initiator-Tightened Surface

INV- 1007 Background The absence of highly porous, uniformly nanoporous surfaces places limitations on handling, fractionating, extracting, recovering and concentrating aqueous and nonaqueous samples of chemicals and biological substances, both soluble and insoluble. For example, if the surface is not highly porous, then a process that depends on...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Roger Giese, Gang Shao

Keywords(s): Analytical Chemistry, Chemistry, Drug Discovery & Development, Research Tool, Screening Tool

Category(s): -Chemistry, -Materials, -Analytical Chemistry, Technology Classifications > 2. Physical Science > Lab tech/equipment