Search Results - biotech

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A Method for Modulating Hydrogen Sulfide Concentrations in the Human Intestine

Engineered bacteria (smart probiotics) have been developed to sense and modify harmful sulfur species and specifically hydrogen sulfide in the gut for the treatment of intestinal diseases such as IBD. https://nu.testtechnologypublisher.com/files/sites/vaibhav-1280x1600.jpeg https://nu.technologypublisher.com/files/sites/adobestock_586108897.jpeg Source:...

Published: 1/27/2025 | Updated: 9/25/2024 | Inventor(s): Justin Hayes, Benjamin Woolston

Keywords(s): Biotech, Gastrointestinal Disease, Medical/Health, Metabolic Engineering, Microbiology

Category(s): -Health, -Microbiology, Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Bio-sensors, -Chemistry, -Biology

Rheology-Informed Neural Networks for complex fluids

INV-21050 Background Many complex and structured fluids exhibit a wide range of rheological responses to different flow characteristics. The ability to predict this complex rheological behavior is essential in better understanding and designing these complex fluids and their processing conditions. Despite the increasing trend in using artificial...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Mohammadamin Mahmoudabadbozchelou, Safa Jamali

Keywords(s): 3D Printer, Adaptive, Artificial intelligence, Biotech, Computational Modeling, Deep learning, Fabrication, Machine Learning, Manufacturing, Materials, Oil/petroleum, Process Engineering

Category(s): -Oil and Gas, Technology Classifications > 3. Computer Science, Technology Classifications > 2. Physical Science, Technology Classifications > 3. Computer Science > AI, Technology Classifications > 3. Computer Science > Neural Networks

Robust Self-Regeneratable Stiff Living Materials

INV-20116 Background Most biomaterials (e.g. wood, silk) found in nature are formed at ambient conditions and degrade naturally to enable a sustainable ecosystem. In contrast, the production of human-made materials (e.g. cement, plastics) requires high temperatures or harsh chemical treatments, while their non-biodegradability unfavorably affects...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Neel Joshi, Anna Duraj-Thatte, Avinash Manjula-Basavanna

Keywords(s): Biomaterials, Biotech, Environment, Living Materials, Manufacturing, Materials, Regeneration

Category(s): Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials, Technology Classifications > 2. Physical Science > Manufacturing

Transwell Millifluidic

INV-19073 Background Many common microfluidic devices experience issues with cell seeding due to their small dimensions and need to be seeded using perfusion. Similarly, the diffusion of nutrients, including oxygen, is limited in many common microfluidics also due to small dimensions. Additionally, while immunofluorescence is the main analytical assay...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Eno Ebong, Ian Harding, Ira Herman, Abigail Koppes, Alex Caraballo

Keywords(s): Biotech, Cardiovascular, Devices

Category(s): Technology Classifications > 2. Physical Science, Technology Classifications > 1. Life Science, Technology Classifications > 2. Physical Science > Lab tech/equipment, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Drug Discovery

Single-cell Pairing Chip for Personalized Immunotherapeutic Screening

INV-19067 Background Natural Killer cells are a type of white blood cell that physically interact with target cancer cells and determine whether to lyse them. The innate heterogeneity of both cancer and NK cells leads to a variety of interactions between pairs of NK-cancer cells. Therefore, single-cell analysis would help in analyzing these interactions...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Yantao Fan, Tania Konry

Keywords(s): Biotech, Cancer

Category(s): -Cancer, -Biology, -Devices, Technology Classifications > 1. Life Science, Diagnostics, Technology Classifications > 1. Life Science > Drug Discovery, Chemistry

Methods and Compositions for Ex Vivo Generation of Developmentally Competent Eggs from Germline Cells Using Autologous Cell Systems

INV-14038 Background According to the latest CDC records, about 12% of women aged 15-44 are suffering from some sorts of infertility; yet, less than 2% of infertile couples actually undergo assisted reproductive therapy (ART). Besides the prohibitive cost of infertility treatments, many factors, including diminished population of immature egg cells...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Jonathan Tilly, Dori Woods

Keywords(s): Biotech, Materials, Medical Device, Method

Category(s): -Materials, -Method, -Biology, Technology Classifications > 1. Life Science > Medical Devices

Macrophage-Targeted Multi-Compartmental Delivery Systems

INV-1028 Background Macrophages are important immune cells in the body that regulate different biological processes involved in inflammatory and infectious diseases. Macrophages originate from the mononuclear phagocyte system (MPS) in the bone marrow. The MPS system comprises of monocytes and tissue, it matures into a larger phagocytic cell called...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Mansoor Amiji, Husain Attarwala, Shardool Jain, Mayur Kalariya

Keywords(s): Biotech, Breast Cancer, Cancer, Chemotherapy, Drug Delivery, Drugs, Health, Medical, Nanomedicine

Category(s): -Biomedical Materials, -Nanomedicine, -Cancer, -Health, Technology Classifications > 1. Life Science > Drug Delivery

Method for Delivery to the Brain of Plasmid DNA Encoding Therapeutic Proteins for CNS Disorders

#0000FF;text-decoration: underline;border-collapse: collapse; } INV-1262 Background Neurodegenerative diseases are debilitating diseases that impose significant financial and social impact and burden. The prevalence of these diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, is progressing...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Barbara Waszczak, Brendan Harmon, Mark Cooper

Keywords(s): Biology, Biotech, Chemistry, Drug Delivery, Health, Medical, Medical/Health, Method, Neurological Disease, Process, Psychiatric Disease, Therapeutic

Category(s): -Biology, -Health, Technology Classifications > 1. Life Science > Drug Delivery, Technology Classifications > 1. Life Science > Therapeutics

Method and Device for Drug Discovery

INV-1253 Background Historically, natural products and microorganisms have been considered as the major sources of new pharmaceutical compounds. However, in recent years, there has been a dramatic drop in natural-based drug discovery from big pharmaceutical companies. The major challenges are the prevailing paradigm for drug discovery in large pharmaceutical...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Slava Epstein

Keywords(s): Analytical Chemistry, Biotech, Drug Discovery & Development, Infectious Disease (including AIDS), Process, Research Tool

Category(s): -Microbiology, -Analytical Chemistry, -Health, Technology Classifications > 1. Life Science > Drug Discovery, Technology Classifications > 2. Physical Science > Lab tech/equipment