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GlycoFix-3 (Structurally and Functionally Repaired Endothelial Glycocalyx, 3rd Edition)

GlycoFix-2 is a chemical formulation that repairs blood vessel linings to prevent heart diseasesGlycoFix-2: Chemical Repair of Blood Vessel Linings for Heart Disease PreventionBackground The endothelial glycocalyx is a sugar mesh coat that serves as a protective barrier for endothelial cells, such as blood vessels. The endothelial glycocalyx can...

Published: 1/27/2025 | Updated: 1/24/2025 | Inventor(s): Eno Ebong, Solomon Mensah, Ronodeep Mitra

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Discovery, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering

Mitochondria transplantation in immune effector cells using droplet microfluidics and a sorter device for activating, modulating, or inhibiting immune cell activity or any cancer or tissue cell type

Search Result Description Here Copy Image URL via instructions below Copy Image URL via instructions below Put in Links to Lab website and USPTO patent: INV-23048 Background: Mitochondria are intracellular organelles that power cells by maintaining cellular homeostasis and contributing to vital cellular functions. They play an...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Tania Konry, Judene Thomas, Agustin De Ganzó

Keywords(s):

Category(s): Technology Classifications > 1. Life Science, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Biotechnology

Site-specific Modification of Antibody through a Tranglutaminase-mediated Conjugation of Glutamine While Maintaining the Core Glycan

Site-specific Modification of Antibody through a Transglutaminase-mediated Conjugation of Glutamine While Maintaining the Core Glycan Technical advancement of site-specific antibody engineering creating more homogenous biologics Institute Reference: INV-21035 Background Antibodies are a predominant class of macromolecules with wide-spread...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Zhaohui Zhou, Amissi Sadiki

Keywords(s): Antibody conjugates, Endoglycosidase, Glycan remodeling, Glycoengineering, Transglutaminase

Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Biotechnology, Diagnostics

Differentiation of Olfactory Mucosa Derived Mesenchymal Stem Cells to Schwann Cells for Peripheral Nerve Repair

rder-collapse: collapse; } INV-21115 Background Peripheral nerve injuries resulting from trauma can be severe and permanently debilitating. Nerve autografting is the current gold standard for the treatment of such injuries. However, after grafting, in approximately one-third of cases, incomplete recovery with poor restoration of function is observed....

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Ryan Koppes, Katelyn Neuman, Abigail Koppes, Aidan Kenny

Keywords(s): Biomedical implants, Cell Culture, Neurological Disease

Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Therapeutics

A benchtop platform to rapidly produce nanofibrous materials

INV-21085 Background Nanofibrous scaffolds can mimic the mechanical and structural properties of the natural extracellular matrix (ECM) and tissues (e.g., collagenous tissues), thereby demonstrating high potential in tissue engineering and regenerative medicine. However, the rapid and reproducible fabrication of biomimetic scaffolds for tissue engineering...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Cassandra Martin, Leila Deravi, Jeffrey Paten

Keywords(s): biomaterial-based scaffold, Collagen, concentric cylinders, fibril alignment

Category(s): -Materials, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering

DNA-based method for rapid capture, detection and analysis of viruses on surfaces

A sensitive and rapid alternative to current viral detection methods INV-21083 Background Thousands of deaths are occurring yearly due to various viral infectious diseases, which has resulted in global public health crisis. COVID‑19 has further brought into focus, the critical need for early detection to prevent transmission, apply effective...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Sara Rouhanifard

Keywords(s): Bio-imaging, COVID-19, Diagnostic tool, virus

Category(s): Technology Classifications > 1. Life Science, Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Diagnostics

METHODS OF MAKING GELS AND FILMS USING CURLI NANOFIBERS

INV-21044 Background The curli system is the primary structural component of bacterial biofilm that promotes bacterial adhesion. This system is composed of highly robust amyloid nanofibers that have self-assembly properties and high resistance to harsh environmental conditions. Such unique properties make these nanofibers attractive for the production...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Neel Joshi

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Drug Delivery, Technology Classifications > 2. Physical Science > Environmental/Clean tech

Biodegradable Implant for Sustained Trans-Nasal Delivery to the Brain

A sustained-release delivery vehicle for the treatment of brain diseases https://nu.technologypublisher.com/files/sites/1-s2.0-s0168365921000365-ga1_lrg.jpg Source: mrithi Padmakumar, Gregory Jones, Grishma Pawar, Olga Khorkova, Jane Hsiao, Jonghan Kim, Mansoor M. Amiji, Benjamin S. Bleier, Minimally Invasive Nasal Depot (MIND) technique...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Mansoor Amiji, Smrithi Padmakumar, Benjamin Bleier

Keywords(s): Biomedical implants, Neurological Disease, Pharmaceutical Composition, Therapeutic

Category(s): -Materials, Technology Classifications > 1. Life Science, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering

Methods and Compositions for Use of Mitochondrial Therapies to Improve Female Reproductive Potential

INV-20078 Background The ability of the female germ cell, called an oocyte, to mature into an egg, fertilize, and develop into a healthy preimplantation embryo required for successful pregnancy (whether fertilization occurs inside (in vivo) or outside (in vitro) the body) is influenced by the quality of the oocyte itself (viz. intrinsic factors)...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Dori Woods, Jonathan Tilly

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering

Reversible Microwells for Single Cells Culture and Recovery

INV-20077 Background Microwells are popular single cell-level culture platforms where small wells of tens of microns in size are able to hold only one cell or cell pairs according to the scope. Arrays of these wells are useful to separate cell populations and culture or image them. However, these wells are monolithic and normally engraved in the...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Giovanni Ugolini, Tania Konry

Keywords(s): Genome, Healthcare Innovation, Immunoengineering, Microarray, Microfluidics, Singe cell

Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering

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