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Neuro-Behavioral Assay for Physiological Evaluation of Water-Soluble Anesthetics

Background The development and use of general anesthetics is a key aspect of modern medicine. However, the current reliance on lipid-soluble general anesthetics presents issues, particularly for elderly patients who often have increased adipose tissue and decreased body water. This demographic can respond poorly to lipid-soluble anesthetics, resulting...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Gunther Zupanc, David Lehotzky

Keywords(s): Anesthesiology, Assays, Chemotherapy, Drug Discovery & Development, High Throughput Screening

Category(s): Technology Classifications > 1. Life Science, Technology Classifications > 1. Life Science > Drug Discovery

Consistent and enhanced production of anti-cancer drugs from the Madagascar periwinkle plant

INV-19070 Background The Madagascar periwinkle plant has been used for vinblastine (VBL) and vincristine (VCR) since the 1960s. These chemical compounds have been listed on “World Health Organization’s Model List of Essential Medicines”. However, due to high cost, low concentration in extracts, and unpredictable supply, the applications...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Carolyn Lee-Parsons, Elisa Peter, Samuel Mortensen

Keywords(s): Agriculture/Horticulture, Chemotherapy, Manufacturing, Process, Renewable

Category(s): Technology Classifications > 1. Life Science > Drug Discovery, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Green Chemistry, Chemistry

Macrophage-Targeted Multi-Compartmental Delivery Systems

INV-1028 Background Macrophages are important immune cells in the body that regulate different biological processes involved in inflammatory and infectious diseases. Macrophages originate from the mononuclear phagocyte system (MPS) in the bone marrow. The MPS system comprises of monocytes and tissue, it matures into a larger phagocytic cell called...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Mansoor Amiji, Husain Attarwala, Shardool Jain, Mayur Kalariya

Keywords(s): Biotech, Breast Cancer, Cancer, Chemotherapy, Drug Delivery, Drugs, Health, Medical, Nanomedicine

Category(s): -Biomedical Materials, -Nanomedicine, -Cancer, -Health, Technology Classifications > 1. Life Science > Drug Delivery