Search Results - drugs

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New Method for Discovery of Bioactive Molecules

INV-20024 Background Microbes are a foundation of the discovery of bioactive molecules because they produce an enormous variety of secondary metabolites, some with desirable activities ranging from antibiotics to anti-inflammatory to anticancer to industrial enzymes. The advent of next-generation sequencing technologies uncovered that microbial genomes...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Slava Epstein

Keywords(s): Antimicrobial, Biomolecules, Cancer, Drugs, Microbiology

Category(s): -Method, Technology Classifications > 1. Life Science > Drug Discovery, Antimicrobial, Technology Classifications > 1. Life Science > Gene sequencing

A probiotic product for detoxification of the recreational drug gamma-hydroxybutyric acid (GHB)

INV-20018 Background GHB is a naturally occurring neurotransmitter and a psychoactive drug. It is a precursor to γ-aminobutyric acid (GABA) and glutamate in certain brain areas. GHB has been used for recreational purposes as a club drug and, in some instances, leads to drug-facilitated sexual assault. When over-dosed, GHB can cause severe...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Yunrong Chai, Yuxuan Qin

Keywords(s): Biomolecules, Drugs, Medical/Health

Category(s): -Analytical Chemistry, -Health

Engineering Bacillus subtilis as a Versatile and Stable Platform for Production of Nanobodies

INV-20012 Background Nanobodies, are a novel class of therapeutic proteins based on single-domain antibody fragments. Due to their small size and unique structure, they have shown great potential as next generation biological drugs. Existing methods for producing these nanobodies have come with certain drawbacks. A common method for production...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Jiahe Li

Keywords(s): Antibody manufacturing, Drugs, Protein production, Therapeutic

Category(s): -Nanomedicine

Macrophage-Targeted Multi-Compartmental Delivery Systems

INV-1028 Background Macrophages are important immune cells in the body that regulate different biological processes involved in inflammatory and infectious diseases. Macrophages originate from the mononuclear phagocyte system (MPS) in the bone marrow. The MPS system comprises of monocytes and tissue, it matures into a larger phagocytic cell called...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Mansoor Amiji, Husain Attarwala, Shardool Jain, Mayur Kalariya

Keywords(s): Biotech, Breast Cancer, Cancer, Chemotherapy, Drug Delivery, Drugs, Health, Medical, Nanomedicine

Category(s): -Biomedical Materials, -Nanomedicine, -Cancer, -Health, Technology Classifications > 1. Life Science > Drug Delivery

Allosteric Modulators of CB1 Cannabinoid Receptors

style-name: Hyperlink;color: #0000FF;text-decoration: underline; } INV-1242 Background Anorexia nervosa (AN) is a major psychiatric eating disorder associated with substantial morbidity and mortality. Its characteristic symptoms include the refusal to maintain minimally normal body weight, an intense fear of becoming fat, and a disturbed perception...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Ganeshsingh Thakur, Pushkar Kulkarni

Keywords(s): Cancer, Chemistry, Drug Discovery & Development, Drugs, Therapeutic

Category(s): -Chemistry, -Pharmaceutical Composition, -Health, Technology Classifications > 1. Life Science > Drug Discovery, Technology Classifications > 1. Life Science > Therapeutics