Search Results - nanomedicine

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Nanococktail for combination therapy, compositions, methods, and uses

INV-20007 Background It is difficult to achieve optimal exposure of all agents in combination therapy with drugs that exhibit different properties. Nanoparticle delivery systems are a well-known means to modify the pharmacokinetics and distribution of drugs. Northeastern researchers have demonstrated that through nanoencapsulation, similar pharmacokinetic...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Srinivas Sridhar, Paige Baldwin, Bijay Singh

Keywords(s): Combination therapy, Drug Delivery, Nanomedicine, Therapeutic, Treatment

Category(s): -Nanotechnology, -Materials

Macrophage-Targeted Multi-Compartmental Delivery Systems

INV-1028 Background Macrophages are important immune cells in the body that regulate different biological processes involved in inflammatory and infectious diseases. Macrophages originate from the mononuclear phagocyte system (MPS) in the bone marrow. The MPS system comprises of monocytes and tissue, it matures into a larger phagocytic cell called...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Mansoor Amiji, Husain Attarwala, Shardool Jain, Mayur Kalariya

Keywords(s): Biotech, Breast Cancer, Cancer, Chemotherapy, Drug Delivery, Drugs, Health, Medical, Nanomedicine

Category(s): -Biomedical Materials, -Nanomedicine, -Cancer, -Health, Technology Classifications > 1. Life Science > Drug Delivery

Man 1-2 Man-PEGylated Derivative as a Tool for in vitro and in vivo Dendritic Cell Targeting

INV-1151 Background The immune system (IS) has a delicate equilibrium between its cells. The most important cells of the IS are the B lymphocytes (BL), macrophages (MO), and dendritic cells (DC), so-called antigen presenting cells (APC). They are the key-linkers between the innate and the adaptive immunity, which is a crucial factor that will lead...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Vladimir Torchilin, Tatiana Levchenko, Juan Pappalardo, Stefano Salmaso, Micaela Toniutti

Keywords(s): Cancer, Chemistry, COVID, Drug Delivery, Genome, Health, Healthcare Innovation, Medical, Nanomedicine, Research Tool

Category(s): -Nanomedicine, -Cancer, -Health, Technology Classifications > 1. Life Science > Drug Delivery, Technology Classifications > 1. Life Science > Therapeutics

Nanopreparation for Co-Delivery of Drugs and siRNA

INV-13004 Background Overexpression of p‑glycoprotein (encoded by MDR1 gene) is often associated with multidrug-resistant cancer. This protein leads to drug resistance by the efflux of chemotherapeutic drugs from the cancerous cells. Small interfering RNA (siRNA), also known as post-transcriptional gene silencer, can suppress the expression of specific...

Published: 1/27/2025 | Updated: 3/21/2024 | Inventor(s): Vladimir Torchilin, Swati Biswas

Keywords(s): Delivery, Drug Delivery, Healthcare Innovation, Medical, Nanomedicine, Nanotechnology, Pharmaceutical Composition, Therapeutic

Category(s): -Nanotechnology, -Nanomedicine, -Pharmaceutical Composition, -Health, Technology Classifications > 1. Life Science > Drug Delivery, Technology Classifications > 1. Life Science > Therapeutics